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Table 4 Univariate and multivariate Cox regression analysis for 1-year RFS of HCC patients baseline

From: Development of nomogram models of inflammatory markers based on clinical database to predict prognosis for hepatocellular carcinoma after surgical resection

Variables 1-year recurrence group
(81)
Non-recurrence group
(279)
Univariate Multivariate
P HR(95% CI) P HR(95% CI)
Gender(male/female) 71(87.7%)/10(12.3%) 227(81.4%)/52(18.6%) 0.170 0.629(0.325-1.220) 0.025 0.455(0.228-0.906)
Diabetes(yes/no) 17(21.0%)/64(79.0%) 30(10.8%)/249(89.2%) 0.016 1.930(1.130-3.297) 0.005 2.210(1.264-3.866)
ALT, U/L (≤50/>50) 66(81.5%)/15(18.5%) 221(79.2%)/58(20.8%) 0.569 0.850(0.485-1.489) 0.001 0.334(0.175-0.635)
PT, seconds (≤13/>13) 70(86.4%)/11(13.6%) 233(83.5%)/46(16.5%) 0.633 0.856(0.453-1.617)
INR(≤1/>1) 20(24.7%)/61(75.3%) 65(23.3%)/214(76.7%) 0.868 0.958(0.578-1.588)
AFP, ng/mL   
≤20 21(25.9%) 146(52.3%)
20-400 21(25.9%) 75(26.9%) 0.044 1.860(1.016-3.406) 0.040 1.923(1.032-3.583)
>400 39(48.2%) 59(20.8%) <0.001 3.520(2.07-5.983) <0.001 2.805(1.602-4.911)
PNI 46.4(26.6,65.8) 49.5(26.5,73.3) 0.004 0.953(0.923-0.985)
APRI 0.30(0.07,4.58) 0.21(0.04,2.16) <0.001 2.072(1.421-3.020) <0.001 2.86(1.764-4.637)
ANRI 13.33(1.51,209.06) 9.8(1.72,63.53) <0.001 1.016(1.007-1.025)
SIRI 0.92(0.21,75.43) 0.83(0.21,51.33) 0.039 1.027(1.001-1.052) 0.021 1.032(1.005-1.060)
MVI(yes/no) 62(76.5%)/19(13.5%) 118(42.3%)/161(57.7%) <0.001 3.572(2.136-5.974) <0.001 2.889(1.662-5.021)
Cirrhosis(yes/no) 42(5.9%)/39(48.1%) 131(47.0%)/148(53.0%) 0.265 1.282(0.829-1.983)
Number of tumours(solitary/multiple) 25(30.9%)/56(69.1%) 45(16.1%)/234(83.9%) 0.003 2.052(1.280-3.289) 0.054 1.621(0.991-2.652)
Tumour diameter,cm 6.49±3.53 4.55±2.78 <0.001 1.154(1.094-1.217) 0.002 1.098(1.034-1.165)
PVTT(yes/no) 19(23.5%)/62(76.5%) 11(3.9%)/268(96.1%) <0.001 4.189(2.504-7.008) 0.001 2.503(1.431-4.378)