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Table 3 Univariate and multivariate Cox regression analysis for RFS of HCC patients baseline

From: Development of nomogram models of inflammatory markers based on clinical database to predict prognosis for hepatocellular carcinoma after surgical resection

Variables Recurrence group
(127)
Non-recurrence group
(233)
Univariate Multivariate
P HR(95% CI) P HR(95% CI)
Gender(male/female) 110(86.6%)/17(13.4%) 188(80.7%)/45(19.3%) 0.130 0.674(0.404-1.123) 0.023 0.544(0.322-0.918)
Diabetes 107(84.3%)/20(15.7%) 206(88.4%)/27(11.6%) 0.099 1.497(0.927-2.416)
ALT, U/L (≤50/>50) 102(80.3%)/25(19.7%) 185(79.4%)/48(20.6%) 0.778 0.939(0.606-1.454) <0.001 0.405(0.245-0.670)
ALBI   
- 2.6 72(56.7%) 164(70.4%)
-2.60 - 1.39 53(41.7%) 67(28.8%) 0.233 0.425(0.104-1.733)
>-1.39 2(1.6%) 2(0.9%) 0.618 0.698(0.170-2.868)
AFP,ng/mL   
≤20 41(32.3%) 126(54.1%)
20-400 29(22.8%) 67(28.7%) 0.174 1.391(0.864-2.239) 0.239 1.335(0.825-2.162)
>400 57(44.9%) 40(17.2%) <0.001 2.764(1.849-4.130) <0.001 2.161(1.402-3.290)
APRI 0.26(0.06,4.58) 0.20(0.04,2.16) <0.001 2.062(1.428-2.976) <0.001 2.494(1.521-4.091)
ANRI 11.87(1.51,209.06) 9.31(1.72,63.53) <0.001 1.016(1.008-1.024)
SIRI 0.92(0.21,75.43) 0.83(0.21,51.33) 0.100 1.023(0.996-1.051)
MVI(yes/no) 95(74.8%)/32(25.2%) 85(36.5%)/148(63.5%) <0.001 3.712(2.483-5.550) <0.001 2.896(1.896-4.424)
Number of tumours(solitary/multiple) 93(73.2%)/34(26.8%) 197(84.5%)/36(15.5%) 0.006 1.737(1.172-2.573) 0.031 1.559(1.041-2.335)
Tumour diameter,cm 6.11±3.39 4.37±2.70 <0.001 1.139(1.091-1.190) 0.004 1.073(1.023-1.125)
Tumour capsule(yes/no) 28(22.0%)/99(78.0%) 33(14.2%)/200(85.8%) 0.047 1.534(1.005-2.339)
PVTT(yes/no) 22(17.3%)/105(82.7%) 8(3.4%)/225(96.6%) <0.001 3.688(2.316-5.872) <0.001 2.737(1.662-4.507)