Table 3 Univariate and multivariate Cox regression analysis for RFS of HCC patients baseline

Gender(male/female)

110(86.6%)/17(13.4%)

188(80.7%)/45(19.3%)

0.130

0.674(0.404-1.123)

0.023

0.544(0.322-0.918)

Diabetes

107(84.3%)/20(15.7%)

206(88.4%)/27(11.6%)

0.099

1.497(0.927-2.416)

–

–

ALT, U/L (≤50/>50)

102(80.3%)/25(19.7%)

185(79.4%)/48(20.6%)

0.778

0.939(0.606-1.454)

<0.001

0.405(0.245-0.670)

ALBI

–

–

–

–

- 2.6

72(56.7%)

164(70.4%)

–

–

–

–

-2.60 - 1.39

53(41.7%)

67(28.8%)

0.233

0.425(0.104-1.733)

–

–

>-1.39

2(1.6%)

2(0.9%)

0.618

0.698(0.170-2.868)

–

–

AFP,ng/mL

–

–

–

–

≤20

41(32.3%)

126(54.1%)

–

–

–

–

20-400

29(22.8%)

67(28.7%)

0.174

1.391(0.864-2.239)

0.239

1.335(0.825-2.162)

>400

57(44.9%)

40(17.2%)

<0.001

2.764(1.849-4.130)

<0.001

2.161(1.402-3.290)

APRI

0.26(0.06,4.58)

0.20(0.04,2.16)

<0.001

2.062(1.428-2.976)

<0.001

2.494(1.521-4.091)

ANRI

11.87(1.51,209.06)

9.31(1.72,63.53)

<0.001

1.016(1.008-1.024)

–

–

SIRI

0.92(0.21,75.43)

0.83(0.21,51.33)

0.100

1.023(0.996-1.051)

–

–

MVI(yes/no)

95(74.8%)/32(25.2%)

85(36.5%)/148(63.5%)

<0.001

3.712(2.483-5.550)

<0.001

2.896(1.896-4.424)

Number of tumours(solitary/multiple)

93(73.2%)/34(26.8%)

197(84.5%)/36(15.5%)

0.006

1.737(1.172-2.573)

0.031

1.559(1.041-2.335)

Tumour diameter,cm

6.11±3.39

4.37±2.70

<0.001

1.139(1.091-1.190)

0.004

1.073(1.023-1.125)

Tumour capsule(yes/no)

28(22.0%)/99(78.0%)

33(14.2%)/200(85.8%)

0.047

1.534(1.005-2.339)

–

–

PVTT(yes/no)

22(17.3%)/105(82.7%)

8(3.4%)/225(96.6%)

<0.001

3.688(2.316-5.872)

<0.001

2.737(1.662-4.507)