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Table 2 Failure Pattern for EAC Patients Treated with VBT alone or EBRT (with or without VBT) in Different Risk Groups

From: Overview of adjuvant radiotherapy on survival, failure pattern and toxicity in stage I to II endometrial carcinoma: a long-term multi-institutional analysis in China

 

Patients (N = 973)

 

Failure mode

Local

No. (%)

p

Regional

No. (%)

p

Local or Regionala

No. (%)

p

Distant

p

Low-risk (N = 284)

 

0.215

 

0.536

 

0.666

 

0.195

VBT alone (N = 189)

1 (0.5)

 

3 (1.6)

 

3 (1.6)

 

6 (3.2)

 

EBRT (with or without VBT) (N = 95)

3 (3.2)

 

0 (0.0)

 

3 (3.2)

 

7 (7.4)

 

Intermediate risk-risk (N = 290)

 

0.990

 

0.605

 

0.433

 

0.796

VBT alone (N = 146)

1 (0.7)

 

1 (0.7)

 

2 (1.4)

 

7 (4.8)

 

EBRT (with or without VBT) (N = 144)

2 (1.4)

 

3 (2.1)

 

5 (3.5)

 

6 (4.2)

 

High-intermediate-risk (N = 185)

 

1.000

 

0.377

 

0.249

 

0.639

VBT alone (N = 99)

2 (2.0)

 

6 (6.1)

 

7 (7.1)

 

6 (6.1)

 

EBRT (with or without VBT) (N = 86)

1 (1.2)

 

2 (2.3)

 

2 (2.3)

 

3 (3.5)

 

High-risk (N = 214)

 

0.218

 

0.178

 

0.016

 

0.147

VBT alone (N = 24)

1 (4.2)

 

2 (8.3)

 

7 (7.1)

 

5 (20.8)

 

EBRT (with or without VBT) (N = 190)

0 (0.0)

 

3 (1.6)

 

2 (2.3)

 

17 (8.9)

 
  1. Note: a “Local or Regional” meant relapse at either local or regional site
  2. Abbreviations: EAC Endometrioid Adenocarcinoma, EBRT External Beam Pelvic Radiotherapy, VBT Vaginal Brachytherapy
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