Table 2 Patient characteristics and patient treatment groups

Sex

male

76

female

24

BMI

median (kg/m²)

24.1 ± 3.7

ECOG

0–1

88

 > 1

7

Primary tumor location

Cardia (AEG I-III)

55

Non-Cardia

44

Chemotherapy treatment

perioperative

29

w/o perioperative

71

Primary tumor resection

yes

48

no

52

R0

36

Grading

G1-2

41

G3-4

58

Number of metastatic sites

1

64

 > 1

36

Best response

Complete Response

6

Partial Response

20

Stable Disease

27

Progressive Disease

30

Central HER2 IHC score

0–1

58

2

16 (11: CISH < 2;

5: CISH ≥ 2)

3

26

Central HER2 CISH score

 < 2

61

 ≥ 2

32

Local HER2 IHC score

0–1

28

2

8

3

45

HER2 targeted treatment

Trastuzumab

55

w/o Trastuzumab

45