Fig. 2

Identification of candidate biomarkers for cetuximab treatment in MKN1 cells. a 49 genes were regulated after 4 h cetuximab and EGF treatment whereas 143 genes were regulated after 24 h cetuximab and EGF treatment. The 22 genes which were regulated after 4 h and 24 h cetuximab and EGF treatment were identified as candidate biomarkers. b The 22 genes which were regulated by cetuximab as well as by EGF treatment after 4 h and 24 h were analyzed using the STRING tool. The colors indicate different functional associations (green: textmining, black: co-expression, pink: experimentally determined)