Fig. 8

Functional enrichment analysis of highly expressed genes (log2 fold-change > 1) in the A) high risk group; and B) low risk group. Pathways enriched in high and low CDI groups: Molecular Function (GO: MF) and Biological Process (GO: BP) of the (C, D) high CDI group and (E, F) the low CDI group. G) Heatmap illustrated the enrichment scores of 20 differentially enriched molecular pathways evaluated by GSVA analysis between low CDI and high CDI patients. Red represented high enrichment scores, and blue represented low enrichment scores. H) PPI network of hubba DEGs obtained from the DEGs network