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Fig. 2 | BMC Cancer

Fig. 2

From: Prognostic value and immune relevancy of a combined autophagy-, apoptosis- and necrosis-related gene signature in glioblastoma

Fig. 2

A) Volcano plot showing the differential expression of genes between high CDI and low CDI patients (p < 0.05, |log2 fold-change|> 1). B) The differential analysis of copy number variations between two groups was visualized by Circos plot, which revealed that compared with the low CDI group, 225 (35.3%) genes were significantly amplified, and 309 (48.4%) were significantly deleted in the high CDI group. Red dots represented amplifications and blue dots represented deletions. C) Left panel: Circos plots of each risk group revealing the amplifications and deletions of chromosomes. Right panel: Boxplots inhibited more burdens of copy number amplifications and deletions in high CDI group. D) Waterfall plots of 15 most frequently mutated DEGs which were altered in 126 GBM samples. E) Waterfall plots showed the top 10 mutated in high risk and low risk group. F) The proportion of mutation status of PTEN, ATRX, TP53 and EGFR in the two groups. G) Violin plots of CDI risk score in individual samples of GBM patients, stratified by IDH, MGMT promoter and TERT mutation status

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