Table 1 Primer sequences

circ_0064288

Forward: 5′-TGGAACAAGCAGCAAATGAG-3′

Reverse: 5′-AATAGCTGGGCAGCAACG-3′

miR-335-5p

Forward: 5′-UGUUUUGAGCGGGGGUCAAGAGC-3’

Reverse: 5′-CUCUCAUUUGCUAUAUUCA-3′

ROCK1

Forward: 5′-AACATGCTGCTGGATAAATCTGG-3′

Reverse: 5′-TGTATCACATCGTACCATGCCT-3′

U6

Forward: 5′-CTCGCTTCGGCAGCACA-3’

Reverse: 5′-AACGCTTCACGAATTTGCGT-3’

GAPDH

Forward: 5′-GGGAAACTGTGGCGTGAT-3’

Reverse: 5′-GAGTGGGTGTCGCTGTTGA-3’