Table 2 Results of univariate analysis of risk factors for EF
Characteristics | EF- | EF+ | OR | 95%CI | P-value |
|---|---|---|---|---|---|
Age (years) | |||||
<70 | 43 | 16 | 1 | ||
≧70 | 34 | 3 | 0.237 | 0.064–0.881 | 0.032 |
Gender | |||||
Female | 21 | 2 | 1 | ||
Male | 56 | 17 | 3.187 | 0.677–14.997 | 0.142 |
T stage | |||||
Non-T4 | 57 | 8 | 1 | ||
T4 | 20 | 11 | 3.919 | 1.380–11.126 | 0.010 |
TNM clinical stage | |||||
IIA-IIB | 25 | 5 | 1 | ||
IIIA-IIIC | 37 | 6 | 0.811 | 0.223–2.948 | 0.750 |
IV | 15 | 8 | 2.667 | 0.736–9.665 | 0.135 |
Location of tumor | |||||
Cervical section | 9 | 1 | 1 | ||
Upper thoracic | 26 | 12 | 4.154 | 0.471–36.609 | 0.200 |
Mid thoracic | 29 | 3 | 0.931 | 0.086–10.095 | 0.953 |
Lower thoracic | 13 | 3 | 2.077 | 0.185–23.298 | 0.553 |
Concurrent CRT in primary RT | 25 | 5 | 0.743 | 0.241–2.293 | 0.605 |
Concurrent CRT in re-RT | 21 | 5 | 0.952 | 0.305–2.971 | 0.933 |
Median the BED in re-RT | 59.47 | 54 | |||
The BED in re-RT (range) | (19.20–72.0) | (31.20–61.20) | 1.056 | 1.991–1.126 | 0.094 |
Median the total BED | 131.47 | 135.72 | |||
The total BED (range) | (84.0–155.15) | (104.60–153.60) | 1.046 | 1.996–1.099 | 0.072 |
Hyperfractionated RT in re-RT | |||||
No | 55 | 18 | 1 | ||
Yes | 22 | 1 | 0.139 | 0.017–1.105 | 0.062 |
Ulcerative EC | |||||
No | 59 | 10 | 1 | ||
Yes | 18 | 9 | 2.95 | 1.039–8.378 | 0.042 |
Esophageal stenosis (cm) | |||||
<0.5 | 20 | 3 | 1 | ||
0.5–1 | 52 | 15 | 1.923 | 0.502–7.363 | 0.340 |
≥ 1 | 5 | 1 | 1.333 | 0.113–15.704 | 0.819 |
Median the length of tumor (cm) | 4 | 5 | |||
The length of tumor (range) (cm) | (2–11) | (3–10) | 1.314 | 1.039–1.663 | 0.023 |
Median the maximum thickness of tumor (mm) | 13.54 | 17.24 | |||
The maximum thickness of tumor (range) (mm) | (7.17–24.87) | (12.75–29.61) | 1.226 | 1.084–1.387 | 0.001 |
Median the time interval between two RTs (months) | 23.33 | 24.4 | |||
The time interval between two RTs (range) (months) | (4.30–238.10) | (8.87–61.27) | 0.989 | 0.974–1.003 | 0.131 |