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Table 5 Multivariate analysis of different characteristics and progression-free survival of LVSI+ population

From: Chemotherapy versus chemoradiotherapy for FIGO stages IB1 and IIA1 cervical squamous cancer patients with lymphovascular space invasion: a retrospective study

Characteristics

P value

HR

95% CI of HR

Lower limit

Upper limit

Tumor size

 < 2 cm

 

Ref.

  

 ≥ 2 cm

.076

.065

.003

1.327

Surgical approach

 Laparotomy

.706

Ref.

  

 Laparoscopic

.992

.000

.000

.000

 Robotic

.404

3.750

.168

83.764

FIGO stage

 IB1

 

Ref.

  

 IIA1

.123

8.073

.567

115.040

Depth of stromal invasion

 Superficial 1/3

.699

Ref.

  

 Middle 1/3

.642

.628

.089

4.446

 Deep 1/3

.588

2.283

.115

45.388

Lymph node metastasis

 Absent

 

Ref.

  

 Present

.017

96.283

2.247

4125.335

Adjuvant therapy

 Chemotherapy

 

Ref.

  

 Chemoradiotherapy

.021

.042

.003

.621

Histopathologic grades

 G1

.022

Ref.

  

 G2

.540

2.722

.110

67.169

 G3

.036

83.727

1.333

5260.175

  1. A Cox proportional hazard regression model for p-values
  2. SE Standard error, HR Hazard ratio, CI Confidence interval, SCC Squamous cell carcinoma antigen, G1 Well differentiated, G2 Moderately differentiated, G3 Poorly or undifferentiated