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Table 4 Univariate analysis of different characteristics and progression-free survival of LVSI+ population

From: Chemotherapy versus chemoradiotherapy for FIGO stages IB1 and IIA1 cervical squamous cancer patients with lymphovascular space invasion: a retrospective study

 

Mean PFS

SE

95% CI of PFS

P

Lower limit

Upper limit

Age

 < 45 years

77.564

3.025

71.635

83.493

.997

 ≥ 45 years

72.486

1.966

68.633

76.339

 

Tumor size

 < 2 cm

76.985

2.594

71.901

82.068

.656

 ≥ 2 cm

72.368

2.048

68.354

76.381

 

SCC (ng/ml)

 < 1.5

75.167

1.985

71.276

79.059

.377

 ≥ 1.5

76.451

2.560

71.434

81.468

 

Surgical approach

 Laparotomy

 Laparoscopic

78.345

2.422

73.597

83.092

.418

 Robotic

65.120

1.842

61.510

68.730

 

FIGO stage

 IB1

80.089

1.665

76.825

83.353

.072

 IIA1

71.688

3.877

64.090

79.287

 

Depth of stromal invasion

 Superficial 1/3

66.870

3.821

59.381

74.359

.153

 Middle 1/3

80.152

1.985

76.262

84.042

 

 Deep 1/3

69.778

2.181

65.504

74.052

 

Lymph node invasion

 Absent

79.135

1.691

75.820

82.450

.061

 Present

62.028

5.345

51.551

72.505

 

Histopathologic grades

 G1

77.000

3.795

69.562

84.438

.001

 G2

80.354

1.502

77.410

83.299

 

 G3

49.667

7.237

35.481

63.852

 

Adjuvant therapy

 Chemotherapy

71.020

4.136

62.913

79.127

.036

 Chemoradiotherapy

80.027

1.681

76.732

83.323

 
  1. Log-rank test for p-values
  2. SE Standard error, CI Confidence interval, SCC Squamous cell carcinoma antigen, G1 Well differentiated, G2 Moderately differentiated, G3 Poorly or undifferentiated