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Table 1 Inclusion and exclusion criteria

From: Single fraction ablative preoperative radiation treatment for early-stage breast cancer: the CRYSTAL study – a phase I/II clinical trial protocol

ELIGIBILITY CRITERIA

INCLUSION CRITERIA

Histologically proven unifocal adenocarcinoma of breast cancer

cT1-cT2 cN0

Age ≥ 18 years old

Good general condition (ECOG 0–2)

Planned surgery (BCS or mastectomy)

Written informed consent

EXCLUSION CRITERIA

Tumor too close to skin or chest wall

Pure non-invasive tumor

Prior RT to the chest

Neoadjuvant chemotherapy

Coagulation, connective, autoimmunitary disorders

Previous malignancies

  1. List of abbreviations: BCS breast conserving surgery, ECOG Eastern Cooperative Oncology Group, RT radiotherapy