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Table 3 Results psychological questionnaires

From: Long-term cognitive, psychosocial, and neurovascular complications of unilateral head and neck irradiation in young to middle-aged adults

Characteristic

Median [IQR]a

P-valueb

N (%) impairedd

BSI

  Depression

-0.39 [-0.79—0.41]

 

4 (13.8)

  Somatization

-0.72 [-0.83—0.39]

 

4 (13.8)

  Fear

-0.69 [-0.80—0.16]

 

5 (17.2)

  Total

-0.64 [-0.86—0.32]

0.28

5 (17.2)

CWS

-0.10 [-0.87—0.67]

0.91

13 (44.8)e

CFQ

  Absentmindedness

-0.32 [-1.27—1.15]

 

3 (10.3)

  Social

-0.38 [-1.63—0.54]

 

1 (3.4)

  Names

0.05 [-0.76—1.00]

 

2 (6.9)

  Orientation

-0.61 [-1.63—0.21]

 

4 (13.8)

  Total

-0.25 [-1.53—0.96]

0.24

3 (10.3)

HADS

  Depression

0.18 [-0.73—0.79]

 

2 (6.9)e

  Anxiety

-0.86 [-1.14—0.03]

 

3 (10.3)e

  Total

-0.22 [-0.86—0.26]

0.26

3 (10.3)

CIS-20R

  Fatigue severity

1.75 [1.21—2.00]

 < 0.001c

15 (51.7)e

  Concentration problems

2.30 [1.70—2.60]

 < 0.001c

25 (86.2)

  Reduced motivation

1.24 [0.76—1.98]

 < 0.001c

9 (31.0)

  Activity

1.64 [1.09—1.98]

 < 0.001c

14 (48.3)

  Total

1.94 [1.74—2.30]

 < 0.001c

23 (79.3)

Impact of Event Scale

  Reliving

-0.33 [-0.55—0.05]

 

0 (0.0)

  Avoidance

0.05 [0.05—0.59]

 

4 (13.8)

  Total

-0.18 [-0.31—0.39]

0.96

1 (3.4)

SHI

  Psychosocial function

-0.24 [-0.24—1.87]

 

7 (24.1)

  Speech function

-0.19 [-0.50—3.53]

0.03

12 (41.4)

  Total

-0.23 [-0.43—3.19]

 

13 (44.8)e

EORTC QLQ C30

  - Functional scales

    Physical

0.57 [-0.46—0.65]

 

2 (6.9)

    Role

0.50 [-0.92—0.59]

 

2 (6.9)

    Emotional

0.04 [-0.76—0.60]

 

3 (10.3)

    Cognitive

0.50 [-1.58—0.50]

 

5 (17.2)

    Social

0.36 [-0.69—0.39]

 

3 (10.3)

    Total

-0.02 [-0.70—0.51]

0.55

2 (6.9)

  - Symptom scales

    Fatigue

0.11 [-0.79—1.16]

 

5 (17.2)

    Nausea

-0.30 [-0.30—0.25]

 

0 (0.0)

    Pain

-0.60 [-0.75—0.64]

 

4 (13.8)

    Dyspnea

-0.42 [-0.42—0.39]

 

2 (6.9)

    Sleeplessness

-0.55 [-0.65—0.63]

 

3 (10.3)

    Eating

-0.31 [-0.31—0.23]

 

4 (13.8)

    Constipation

-0.28 [-0.38—0.28]

 

2 (6.9)

    Diarrhea

-0.27 [-0.32—0.27]

 

3 (10.3)

    Financial

-0.28 [-0.28—0.23]

 

2 (6.9)

    Total

-0.10 [-0.36—0.25]

0.60

1 (3.4)

  - Global

0.35 [-0.11—1.05]

0.07

2 (6.9)

  1. a Data are expressed as median [interquartile-range] based on normative data with a mean Z-score of zero. Impaired Z-score is defined as Z ≤ -1.65 (performance worse than 95% of the norm population); b Not Benjamini–Hochberg adjusted p-values are shown; c Statistically significant change compared to normative data after Benjamini–Hochberg correction; d based on Z-score ≥ 1.65 or, if marked with e, on a predefined clinical cut-off value (i.e. BSI-total: ≥ 14, HADS-depression ≥ 11, HADS-anxiety ≥ 11,CIS-20R fatigue severity ≥ 35, and SHI-total ≥ 6). BSI  Brief Symptom Inventory, CWS Cancer Worry Scale, CFQ Cognitive Failure Questionnaire, HADS  Hospital Anxiety and Depression Scale  CIS-20R  Checklist Individual Strength-20R, SHI  Speech Handicap Index, EORTC QLQ C30  European Organization for Research and Treatment for Cancer Quality of Life Questionnaire