Table 1 Patient characteristics
Characteristic | n = 29 |
|---|---|
Demographics | |
  Men, n (%) | 13 (44.8) |
  Median age, years [IQR] | 41.0 [33.5—47.0] |
  Median age at treatment, years [IQR] | 35.0 [23.5—39.5] |
  Median follow-up after RT, years [IQR] | 9.2 [7.3—12.9] |
Diagnosis, n (%) | |
  Carcinoma of parotid | 7 (24.1) |
  Pleiomorphic adenoma of parotid | 8 (27.5) |
  Carcinoma of oropharynx | 2 (6.9) |
  Lymphoma (primary) | 8 (27.6) |
  Others a | 4 (13.8) |
Radiotherapy | |
  Total dose, Gy (median [IQR], min–max) | 50 [37.0—66.0], 26—100 b |
Chemotherapy, n (%) | |
  Total | 10 (34.5) |
  Anthracycline | 9 (31.0) |
  Platinum-based | 2 (6.9) |
  Alkylating | 8 (27.5) |
  Others | 8 (27.5) |
Surgery | |
  (Partial) parotidectomy | 16 (55.2) |
  Cervical lymph node dissection | 5 (17.2) |
  Resection tongue(edge) | 2 (6.9) |
  (Hemi)mandibulectomy | 2 (6.9) |
  Others | 4 (13.8) |
Tumor laterality, n (%) | |
  Left | 18 (62.1) |
  Right | 11 (37.9) |
CVD risk factors, n (%) | |
  Smoking | |
    Current | 6 (20.7) |
    Former | 5 (17.2) |
    Pack years, median [IQR] | 15.0 [5.0—25.0] |
  Positive family history of CVD | 8 (27.6) |
  Chronic daily stress | 10 (34.5) |
  Hypertension | 8 (27.6) |
  Hypercholesterolemia | 10 (43.5) |
  Overweight | 12 (41.4) |
  Diabetes | 1 (3.4) |
  Chronic renal insufficiency | 3 (11.5) |
Number of CVD risk factors, n (%) | |
  0 | 3 (10.3) |
  1 | 6 (20.7) |
  2 | 11 (37.9) |
   ≥ 3 | 9 (31.0) |
Education level, median [IQR] | 6.0 [5.0—7.0] |
Manual laterality | |
  Right | 23 (79.3) |
  Left | 5 (17.2) |
  Bimanual | 1 (3.4) |