Fig. 2

Expression levels of B7-H3 and B7-H4 in variously differentiated PAAD tissues. A Representative microphotographs revealing low B7-H3 expression in well-differentiated tissues and high B7-H3 expression in moderate and poor-differentiated tissues using IHC staining. Brown, B7-H3. Blue, haematoxylin. Bar = 200 μm. B The semi-quantitative analysis of B7-H3 in variously differentiated PAAD tissues. B7-H3 was significantly up-regulated in moderate and poor-differentiated tissues compared with well-differentiated tissues. C Representative microphotographs revealing low B7-H4 expression in well-differentiated tissues and high B7-H4 expression in moderate and poor-differentiated tissues using IHC staining. Brown, B7-H4. Blue, haematoxylin. Bar = 200 μm. D The semi-quantitative of B7-H4 in variously differentiated PAAD tissues. B7-H4 was significantly up-regulated in moderate and poor-differentiated tissues compared with well-differentiated tissues. E B7-H3 mRNA expression was various in differently differentiated PAAD tissues in the TCGA database. F B7-H4 mRNA expression showed no changes in differently differentiated PAAD tissues in the TCGA database