SNCA correlates with immune infiltration and serves as a prognostic biomarker in lung adenocarcinoma

BMC Cancer

Table 2 Patient clinical characteristics at presentation

Clinical characteristics		Total (78)	%	High	Low	P-Value
Age	> = 65	33	42.3	19	14	0.252
Age	< 65	45	57.7	20	25
Gender	Male	42	53.8	17	25	0.069
Gender	Female	36	46.2	22	14
Stage	I	23	37.1	14	9	0.752
	II	17	27.4	9	8
	III/IV	22	35.5	11	11
T stage	T1	21	28.4	13	8	0.091
	T2	35	47.3	13	22
	T3	12	16.2	7	5
	T4	6	8.1	5	1
N stage	N0	30	62.5	18	12	0.462
	N1	12	25	6	6
	N2/N3	6	12.5	2	4
Pleural invasion	Negative	67	85.9	33	34	0.745
Pleural invasion	Positive	11	14.1	6	5
ALK	Negative	65	87.8	34	31	0.658
ALK	Positive	9	12.2	4	5
EGFR	Negative	59	75.6	26	33	0.065
EGFR	Positive	19	24.4	13	6

Seventy-eight patients with lung adenocarcinoma with complete follow-up data were selected as the research objects. The staging was in accordance with the 7th edition of the AJCC Cancer Staging Manual. The follow-up ended in July 2016. The Pearson correlation coefficient by SPSS was used to analyze the relationships among SNCA expression and clinical characteristics of LUAD patients

ISSN: 1471-2407