Table 1 Association between POLD1 expression and the clinicopathological variables in HCC patients (n = 339)
From: A Comprehensive Prognostic Analysis of POLD1 in Hepatocellular Carcinoma
Variables | POLD1 Expression | P | |
|---|---|---|---|
High (n = 172) | Low (n = 167) | ||
Age (year) | |||
< 65 | 112 (65.1%) | 96 (57.5%) | 0.183 |
≥ 65 | 60 (34.9%) | 71 (42.5%) | |
Gender | |||
Male | 112 (65.1%) | 119 (71.3%) | 0.273 |
Female | 60 (34.9%) | 48 (28.7%) | |
Family history of cancer | |||
No | 104 (60.5%) | 92 (55.1%) | 0.153 |
Yes | 42 (24.4%) | 56 (33.5%) | |
Unknown | 26 (15.1%) | 19 (11.4%) | |
TNM stage | |||
I | 71 (41.3%) | 99 (59.3%) | < 0.001 |
II | 47 (27.3%) | 37 (22.2%) | |
III | 54 (31.4%) | 27 (16.2%) | |
IV | 0 (0%) | 4 (2.4%) | |
Histologic grade | |||
G1–G2 | 88 (51.2%) | 124 (74.3%) | < 0.001 |
G3–G4 | 83 (48.3%) | 42 (25.1%) | |
Unknown | 1 (0.6%) | 1 (0.6%) | |
Ishak score | |||
0–4 | 61 (35.5%) | 63 (37.7%) | 0.013 |
5–6 | 28 (16.3%) | 46 (27.5%) | |
Unknown | 83 (48.3%) | 58 (34.7%) | |
Child–Pugh grade | |||
A | 103 (59.9%) | 104 (62.3%) | 0.331 |
B-C | 8 (4.7%) | 13 (7.8%) | |
Unknown | 61 (35.5%) | 50 (29.9%) | |
Vascular invasion | |||
None | 93 (54.1%) | 100 (59.9%) | 0.230 |
Micro | 41 (23.8%) | 43 (25.7%) | |
Macro | 7 (4.1%) | 7 (4.2%) | |
Unknown | 31 (18.0%) | 17 (10.2%) | |
Alpha fetoprotein | |||
Negative | 49 (28.5%) | 94 (56.3%) | < 0.001 |
Positive | 82 (47.7%) | 38 (22.8%) | |
Unknown | 41 (23.8%) | 35 (21.0%) | |
Residual tumor | |||
R0 | 151 (87.8%) | 150 (89.8%) | 0.761 |
R1-R2 | 6 (3.5%) | 6 (3.6%) | |
Unknown | 15 (8.7%) | 11 (6.6%) | |