Fig. 3

Downregulation of lncRNA AC087388.1 remarkably decreased cell viability. A MTT assay for SW-48 cell. B MTT assay for HT-29 cell. C Apoptosis fraction graph of the cells, apoptotic cell death was measured by annexin V staining after 24 h. Annexin V-positive cells are considered early apoptotic, whereas PI uptake indicates necrosis. Cells positive for both stains are considered apoptotic cells. D The percentage of the viable, necrosis, early, and late apoptosis