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Table 1 Comparison of p-AKT, p-mTOR, p-S6, and p-4E-BP1 expression levels between PCNSL samples and reactive hyperplastic lymph node samples (the control group)

From: The PI3K/AKT/mTOR signaling pathway is aberrantly activated in primary central nervous system lymphoma and correlated with a poor prognosis

Protein

PCNSL

Control

P value

(n = 7)

(n = 6)

p-AKT

0.352 ± 0.104

0.346 ± 0.168

0.935

p-mTOR

0.489 ± 0.268

0.065 ± 0.030

0.006*

p-S6

0.986 ± 0.324

0.378 ± 0.344

0.007*

p-4E-BP1

1.557 ± 0.668

0.526 ± 0.592

0.014*

  1. Data are shown as the mean ± SD; * represents a statistically significant difference