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Fig. 2 | BMC Cancer

Fig. 2

From: Mammary tumors alter the fecal bacteriome and permit enteric bacterial translocation

Fig. 2

Mammary tumors impair markers of colonic barrier integrity. Tumor-bearing mice have decreased colonic expression of tight junction proteins Claudin 1 (Cldn1, A) and Occludin (Ocln) (B). Resected mice have reduced Ocln expression and tend to have reduced expression of Cldn1. Tumor mice also have increased circulating lipopolysaccharide binding protein (C), a marker of bacterial translocation. * = p < 0.05, ** = p < 0.01, *** = p < 0.0001, NS=Not Significant, by ANOVA and post-hoc LSD

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