Table 2 Reviewed panels for bladder cancer detection

1

TIMP3,APC,CDKN2A,MLH1,ATM,RARB,CDKN2B,HIC1,CHFR,BRCA1,CASP8,CDKN1B,PTEN,BRCA2,CD44,RASSF1,DAPK1,FHIT,VHL,ESR1,TP73,IGSF4,GSTP1,CDH13

MS-MLPA

–

–

1.00

0.83

0.89

[17]

2

HIC1,RASSF1,GSTP1

MS-MLPA

0.66

0.78

0.91

0.67

0.76

[17]

3

HOXA9,ISL1

qMSP

0.91

0.44

0.99

0.71

0.78

[18]

4

PCDH17,POU4F2

qMSP

0.94

0.90

1.00

0.73

0.81

[19]

5

E2F3,CCND1,UTP6,CDADC1,SLC35E3,METRNL,TPCN2,NACC2,VGLL4,PTEN

metadata

–

–

0.98

0.63

0.73

[20]

6

CDH13,CFTR,NID2,SALL3,TMEFF2,TWIST1,VIM2

pyrosequencing

–

–

1.00

0.63

0.76

[21]

7

CFTR,SALL3,TWIST1

pyrosequencing

0.31

0.90

1.00

0.65

0.77

[21]

8

SOX1,TJP2,MYOD,HOXA9_1,HOXA9_2,VAMP8,CASP8,SPP1,IFNG,CAPG,HLADPA1,RIPK3

pyrosequencing

1.00

1.00

1.00

0.74

0.84

[21]

9

ZNF671,SFRP1,IRF8

qMSP

0.84

0.96

1.00

0.59

0.74

[22]

10

TWIST1,NID2

MSP

0.93

0.96

1.00

0.61

0.76

[23]

11

VIM,TMEFF2,GDF15

qMSP

1.00

0.94

1.00

0.54

0.71

[24]

12

VIM,TMEFF2,GDF15,HSPA2

qMSP

1.00

0.94

1.00

0.54

0.71

[24]

13

SALL3,CFTR,ABCC6,HPR1,RASSF1A,MT1A,ALX4,CDH13,RPRM,MINT1,BRCA1

MSP

0.87

0.92

1.00

0.73

0.83

[25]

14

SALL3,CFTR,MT1A,HPP1,ABCC6,RASSF1A,CDH13,RPRM,MINT1,BRCA1,SFRP1

MSP

0.73

0.92

1.00

0.72

0.83

[26]

15

SALL3,CFTR,MT1A,HPP1,ABCC6,RASSF1A,CDH13,RPRM,MINT1,BRCA1

MSP

0.80

0.90

1.00

0.70

0.81

[26]

16

p14ARF,p16INK4A,RASSF1A,DAPK,APC

MSP

–

0.91

1.00

0.64

0.77

[27]

17

RARβ,DAPK,CDH1,p16

MSP

0.76

0.91

1.00

0.66

0.79

[28]

18

HOXA9,PCDH17,POU4F2,ONECUT2

qMSP

0.73

0.91

1.00

0.71

0.82

[29]

19

PENK

qMSP

0.88

0.89

0.96

0.68

0.78

#

P3

PCDH17,POU4F2,PENK

–

–

–

1.00

0.71

0.82

–