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Table 1 Baseline clinical characteristics of all patients

From: Massive digital gene expression analysis reveals different predictive profiles for immune checkpoint inhibitor therapy between adenocarcinoma and squamous cell carcinoma of advanced lung cancer

Patient characteristics

All patients

(n = 42)

%

Age (years)

 Median (range)

69 (43–85)

 

 < 70

23

54.8

 ≥70

19

45.2

Sex

 Male

34

81.0

 Female

8

19.0

Smoking history

 Never

5

11.9

 Current or former

37

88.1

Histology

 Adenocarcinoma

20

47.6

 Squamous cell carcinoma

22

52.4

EGFR mutation status

 Del-19

1

2.4

 Exon 18

1

2.4

 Wild type

22

52.4

 Unknown

18

42.8

PD-L1 (TPS)

 0

2

4.8

 5–49

3

7.1

 ≥50

5

11.9

 Unknown

32

76.2

Number of previous chemotherapy regimen

 1

22

52.4

 2

8

19.0

 ≥3

12

28.6

Number of administrations

 Median (range)

9 (1–64)

 

 1–5

11

26.2

 6–10

13

31.0

 11–30

10

23.8

 ≥31

8

19.0

Type of specimen material

 Brush

29

69.1

 TBB

8

19.0

 FNA (Lymph node)

4

9.5

 CTGB

1

2.4

  1. EGFR epidermal growth factor receptor, Del-19 19 deletion, PD-L1 programmed cell death ligand 1, TPS Tumor Proportion Score, TBB transbronchial biopsy, FNA fine-needle aspiration, CTGB computed tomography guided biopsy