Table 3 Univariate and multivariate analysis of prognostic factor for overall survival

Age

1.01 (0.99–1.03)

–

ECOG PS

–

 0

Reference

 1–2

1.39 (0.67–2.89)

Child-Pugh class

< 0.001

 A

Reference

Reference

 B

3.98 (2.29–6.92)

3.13 (1.73–5.67)

Etiology

–

 HBV

Reference

 Others

1.06 (0.64–1.75)

BCLC stage

0.860

 0

Reference

Reference

 A

1.71 (1.08–2.69)

0.94 (0.49–1.80)

Tumor size

1.29 (1.04–1.61)

1.26 (0.99–1.59)

0.059

Alpha-fetoprotein

0.341

 ≤ 20 ng/mL

Reference

Reference

 >  20 ng/mL

1.47 (0.94–2.30)

1.25 (0.79–1.98)

Number of prior treatment sessions

1.04 (0.98–1.10)

–

BED

0.97 (0.95–0.98)

0.98 (0.96–1.00)

0.014

CR at 3 months

–

 Yes

Reference

 No

1.33 (0.83–2.14)

anyCR^a

0.094

 Yes

Reference

Reference

 No

2.38 (0.96–5.93)

2.23 (0.87–5.68)