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Table 2 List of top 20 upregulated and downregulated transcripts in exosomal RNA from HPV-positive cells

From: Transcriptome analysis of cervical cancer exosomes and detection of HPVE6*I transcripts in exosomal RNA

Fragment Id

Gene Name

Gene Description

Enrichment Score (FPKM)

P value

   

C33a-Exo

SiHa-Exo

HeLa-Exo

 

Upregulated

 MSTRG.367518.1

TBC1D9

TBC1 domain family member 9

0.0

318.0

0.0

1.87E-09

 MSTRG.344677.1

EVC2

EvC ciliary complex subunit 2

0.0

1313.3

0.0

3.99E-11

 MSTRG.133308.1

-

-

0.0

0.0

4341.5

8.89E-12

 ENST00000423783.1

ACTG1P24

-

0.0

3.8

3570.2

6.77E-05

 ENST00000478808.2

USP30-AS1

-

3.2

10.6

7285.6

0.000154

 ENST00000532136.2

OR5AM1P

-

4.7

30.0

9612.9

0.000111

 MSTRG.477223.1

RP11-11N9.4

-

17.4

195.9

20881.6

0.000136

 MSTRG.72906.1

-

-

0.0

28.8

1423.9

0.00012

 MSTRG.15951.1

NFIA

nuclear factor I A

0.0

1.9

2700.7

0.00013

 MSTRG.306972.1

-

-

3.2

5.0

5714.5

0.000327

 MSTRG.197855.1

-

-

0.0

40.1

1029.7

0.000169

 MSTRG.42334.1

-

-

0.0

294.2

154.7

0.000437

 MSTRG.376580.1

-

-

0.0

16.3

633.7

0.000542

 MSTRG.349353.1

-

-

0.0

50.7

414.9

0.000613

 MSTRG.292085.1

CH507-513H4.1

-

1.6

2.5

2853.5

0.000539

 ENST00000540040.2

MTRNR2L1

MT-RNR2-like 1

58.5

380.0

35309.4

0.000563

 MSTRG.62777.1

-

-

4.7

47.6

3485.3

0.000487

 MSTRG.117243.1

ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

3.2

27.5

2961.0

0.000436

 MSTRG.7924.1

LUZP1

leucine zipper protein 1

1.6

83.9

1241.0

0.00037

 ENST00000545075.2

MTRNR2L10

MT-RNR2-like 10

24.5

213.5

19438.8

0.000315

Downregulated

 MSTRG.496845.1

RP11-661A12.12

-

69.6

0.0

0.0

0.016636

 MSTRG.304551.1

APOBEC3A

apolipoprotein B mRNA editing enzyme catalytic subunit 3A

104.3

0.0

0.0

0.005624

 MSTRG.223388.1

-

-

59.3

0.0

0.0

0.024676

 MSTRG.198709.1

-

-

61.6

0.0

0.0

0.022445

 MSTRG.226490.1

CTD-2189E23.1

-

60.9

0.0

0.0

0.023159

 MSTRG.344367.1

-

-

95.6

0.0

0.0

0.007161

 MSTRG.2801.1

-

-

58.5

0.0

0.0

0.025481

 MSTRG.219083.1

OACYLP

-

58.5

0.0

0.0

0.025481

 MSTRG.355211.1

UGT2B17

UDP glucuronosyltransferase family 2 member B17

57.7

0.0

0.0

0.02632

 MSTRG.431828.1

-

-

56.9

0.0

0.0

0.027195

 MSTRG.244195.1

-

-

55.3

0.0

0.0

0.029056

 MSTRG.277817.1

AGAP1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

56.9

0.0

0.0

0.027195

 MSTRG.281076.1

SNAP25-AS1

SNAP25 antisense RNA 1

50.6

0.0

0.0

0.035696

 MSTRG.195412.1

MYO15A

myosin XVA

55.3

0.0

0.0

0.029056

 MSTRG.545174.1

-

-

56.9

0.0

0.0

0.027195

 MSTRG.278737.1

THAP4

THAP domain containing 4

83.8

1.3

0.0

0.028536

 MSTRG.304552.1

APOBEC3A

apolipoprotein B mRNA editing enzyme catalytic subunit 3A

88.5

0.6

0.0

0.015573

 MSTRG.2807.1

-

-

86.9

0.0

0.0

0.009282

 MSTRG.422941.1

FILIP1

filamin A interacting protein 1

93.3

0.0

0.0

0.007671