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Table 2 Clinical and pathological characteristics of 141 rectal cancer patients with or without pathological LPNM before and after matching

From: Prognostic significance of lateral pelvic lymph node dissection for middle-low rectal cancer patients with lateral pelvic lymph node metastasis: a propensity score matching study

Variables

Original cohort

Matched cohort

LPNM (n = 29)

Non-LPNM (n = 112)

P

LPNM (n = 29)

Non-LPNM (n = 29)

P

Age (years, mean ± SD)

57.5 ± 11.7

56.2 ± 10.4

0.551

57.5 ± 11.7

58.6 ± 10.1

0.632

 Gender

  

0.462

  

0.594

  Male

18 (62.1)

61 (54.5)

 

18 (62.1)

16 (55.2)

 

  Female

11 (37.9)

51 (45.5)

 

11 (37.9)

13 (44.8)

 

BMI (kg/m2, mean ± SD)

24.3 ± 3.0

25.0 ± 3.2

0.295

24.3 ± 3.0

24.5 ± 2.5

0.930

CEA level (ng/mL, mean ± SD)

15.0 ± 32.0

8.4 ± 15.1

0.124

15.0 ± 32.0

12.9 ± 22.5

0.811

CA19-9 level (ng/mL, mean ± SD)

47.9 ± 101.8

19.0 ± 17.3

0.169

47.9 ± 101.8

35.2 ± 41.4

0.373

ASA category

  

0.580

  

1.000

  I-II

26 (89.7)

106 (94.6)

 

26 (89.7)

27 (93.1)

 

  III-IV

3 (10.3)

6 (5.4)

 

3 (10.3)

2 (6.9)

 

Preoperative treatment

16 (55.2)

58 (51.8)

0.745

16 (55.2)

17 (58.6)

0.791

Distant metastasis

4 (13.8)

8 (7.2)

0.441

4 (13.8)

4 (13.8)

1.000

Surgical approach

  

0.651

  

1.000

  Open

1 (3.4)

9 (8.0)

 

1 (3.4)

2 (6.9)

 

  Laparoscopic

28 (96.6)

103 (92.0)

 

28 (96.6)

27 (93.1)

 

Histology

  

0.047

  

0.588

  Moderate

16 (55.2)

83 (74.1)

 

17 (58.6)

19 (65.5)

 

  Poor/Mucinous/signet

13 (44.8)

29 (25.9)

 

12 (41.4)

10 (34.5)

 

pT stage

  

0.012

  

0.666

  T1-T2

2 (6.9)

33 (29.5)

 

2 (6.9)

4 (13.8)

 

  T3-T4

27 (93.1)

79 (70.5)

 

27 (93.1)

25 (86.2)

 

pN stage

  

 < 0.001

  

0.636

   N0

3 (10.3)

56 (50.0)

 

3 (10.3)

5 (17.3)

 

   N1

12 (41.4)

33 (29.5)

 

12 (41.4)

13 (44.8)

 

   N2

14 (48.3)

23 (20.5)

 

14 (48.3)

11 (37.9)

 

Perineural invasion

14 (48.3)

41 (36.6)

0.251

14 (48.3)

12 (41.4)

0.597

Lymphatic invasion

13 (44.8)

28 (25.0)

0.036

13 (44.8)

11 (37.9)

0.594

Vascular invasion

13 (44.8)

33 (29.5)

0.116

13 (44.8)

10 (34.5)

0.421

Mesorectal lymph nodes harvested

15.6 ± 8.2

18.7 ± 10.2

0.137

15.6 ± 8.2

17.3 ± 9.6

0.691

LPLNs harvested

9.3 ± 5.5

9.9 ± 6.1

0.773

9.3 ± 5.5

10.9 ± 6.4

0.573