Fig. 3

FCER1G was abundantly expressed in ccRCC and indicated poor prognosis in patients receiving anti-PD-1 treatment. A Kaplan–Meier curves revealing that high expression of STAC3 and FCER1G were related to poor overall survival in patients with ccRCC from TCGA-KIRC. B The violin plot shows that STAC3 has the lowest expression levels among the five candidate DEGs. C The Kaplan–Meier survival curve shows that high FCER1G expression was related to poor overall survival in patients treated with Nivolumab in the CheckMate 025 clinical trial, but not in D those treated with Everolimus in the same research study. ccRCC, clear cell renal cell carcinoma; DEG, differentially expressed gene; FCER1G, Fc fragment of IgE receptor Ig; PD-1, programmed cell death 1; STAC3, SH3 and cysteine rich domain 3; TCGA-KIRC, The Cancer Genome Atlas-kidney renal clear cell carcinoma