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Fig. 3 | BMC Cancer

Fig. 3

From: Functional interaction between S100A1 and MDM2 may modulate p53 signaling in normal and malignant endometrial cells

Fig. 3

Changes in proliferation following overexpression and knockdown of S100A1 in Hec6 or Hec251 cells. A, B Upper left: two independent clones of stable H6-S100A1 (A) and H251-shS100A1 cells (B), as well as controls, were seeded at low density. The cell numbers are presented as mean ± SDs. P0, P3, P6, and P9 are 0, 3, 6, and 9 days after cell passage, respectively. Lower left: FACS analyses of stable H6-S100A1, H251-shS100A1 and control cells at 3 days after seeding (P3). Right: western blot analysis of the indicated proteins in stable H6-S100A1 cells (A), H251-shS100A1 cells (B), and controls following re-stimulation of serum-starved (24 h) cells with 10% serum for the indicated times. The p53 and MDM2 bands are indicated by arrows

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BMC Cancer

ISSN: 1471-2407

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