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Fig. 3 | BMC Cancer

Fig. 3

From: Circular RNA hsa_circ_0000277 promotes tumor progression and DDP resistance in esophageal squamous cell carcinoma

Fig. 3

Knockdown of hsa_circ_0000277 suppressed cell proliferation, colony formation, cell cycle, and DDP resistance in ESCC cells. A Hsa_circ_0000277 was detected through RT-qPCR in EC9706 and KYSE30 cells with transfection of shRNA vectors (sh-NC, sh-circ_0000277#1 or sh-circ_0000277#2). B–G Cellular proliferation (B–C), colony formation (D–E), and cell cycle (F–G) were respectively assessed by CCK-8, colony formation assay and flow cytometry. H–J IC50 of DDP was assayed by CCK-8. K–L The apoptotic effect of hsa_circ_0000277 downregulation on ESCC was analyzed by flow cytometry under DDP treatment. *P < 0.05

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