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Fig. 3 | BMC Cancer

Fig. 3

From: Circular RNA hsa_circ_0000277 promotes tumor progression and DDP resistance in esophageal squamous cell carcinoma

Fig. 3

Knockdown of hsa_circ_0000277 suppressed cell proliferation, colony formation, cell cycle, and DDP resistance in ESCC cells. A Hsa_circ_0000277 was detected through RT-qPCR in EC9706 and KYSE30 cells with transfection of shRNA vectors (sh-NC, sh-circ_0000277#1 or sh-circ_0000277#2). BG Cellular proliferation (BC), colony formation (DE), and cell cycle (FG) were respectively assessed by CCK-8, colony formation assay and flow cytometry. HJ IC50 of DDP was assayed by CCK-8. KL The apoptotic effect of hsa_circ_0000277 downregulation on ESCC was analyzed by flow cytometry under DDP treatment. *P < 0.05

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