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Table 2 Characterization of included breast cancer patients who were eligible for screening and description of initial treatment phase by mode of detection

From: Initial and ten-year treatment patterns among 11,000 breast cancer patients undergoing breast surgery—an analysis of German claims data

 

All

Mode of detection

Screening participants

Unscreened (eligible)

Screen-detecteda

Interval-detected

6065

(100%)

2049

(33.8%)

476

(7.8%)

3540

(58.4%)

Age at diagnosis

 Mean age at diagnosis (SD)

61.2

(6.0)

62.0

(5.8)

61.9

(6.0)

60.6

(6.0)

  < 50 years at diagnosis

N/A

(0%)

N/A

(0%)

N/A

(0%)

N/A

(0%)

 50–69 years at diagnosis

5950

(98.1%)

1970

(96.1%)

440

(92.4%)

3540

(100%)

 70–79 years at diagnosis

115

(1.9%)

79

(3.9%)

36

(7.6%)

N/A

(0%)

 80 + years at diagnosis

N/A

(0%)

N/A

(0%)

N/A

(0%)

N/A

(0%)

Stage at diagnosis

 No affected lymph nodes/distant metastases

5015

(82.7%)

1807

(88.2%)

392

(82.4%)

2816

(79.5%)

 Affected lymph nodes only

788

(13.0%)

206

(10.1%)

72

(15.1%)

510

(14.4%)

 Distant metastases

262

(4.3%)

36

(1.8%)

12

(2.5%)

214

(6.0%)

Breast surgeryb

 Breast conserving surgery only

4608

(76.0%)

1756

(85.7%)

348

(73.1%)

2504

(70.7%)

 Mastectomy

1457

(24.0%)

293

(14.3%)

128

(26.9%)

1036

(29.3%)

 Both types of surgery

610

(10.1%)

151

(7.4%)

61

(12.8%)

398

(11.2%)

 Two or more surgeries

1606

(26.5%)

494

(24.1%)

145

(30.5%)

967

(27.3%)

Neoadjuvant systemic therapy

 Yes

501

(8.3%)

43

(2.1%)

43

(9.0%)

415

(11.7%)

Adjuvant systemic therapyc

 Cytostatic drugs

2758

(45.5%)

771

(37.6%)

236

(49.6%)

1751

(49.5%)

 Monoclonal antibody

57

(0.9%)

6

(0.3%)

4

(0.8%)

47

(1.3%)

 Hormone therapy

2823

(46.5%)

1086

(53.0%)

200

(42.0%)

1537

(43.4%)

Radiotherapyd

 Within ten months after breast surgery

4866

(80.2%)

1708

(83.4%)

381

(80.0%)

2777

(78.4%)

 Before breast surgery

38

(0.6%)

3

(0.1%)

2

(0.4%)

33

(0.9%)

  1. SD standard deviation, N/A not applicable
  2. aBreast cancer was classified as “screen-detected” if a screening mammography and multidisciplinary case conference were coded in relevant time periods before and surrounding the diagnosis. It was classified as “interval-detected” if the woman had a screening mammography in the regular interval (two years) before diagnosis, but the criteria for “screen-detected” were not fulfilled. Patients without a screening mammography in the regular interval and aged 50–69 years at diagnosis were classified as unscreened, but eligible. The remaining patients were classified as “unscreened and ineligible” (not included in this table).Some patients may be diagnosed, e.g., at age 70 and screened at age 69
  3. bWithin one year after diagnosis. Mastectomy includes those with both types of surgery. “Two or more surgeries” refers to additional breast conserving surgery/mastectomy in the first year after the first surgery
  4. cThis refers to adjuvant systemic therapy initiated within four months after breast surgery
  5. dThis refers to radiotherapy initiated within ten months after breast surgery
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BMC Cancer

ISSN: 1471-2407

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