Skip to main content

Table 3 According to the results of GWAS, SNPs with p-value < 5E-07 were selected for replication testing in another population

From: Genome-wide association study of serum tumor markers in Southern Chinese Han population

Tumor maker

Gene

SNP ID

Chr

Position

Alleles

MA

MAF

Func

β

SE

p

FDR

CA125

GCFC2; LRRTM4

rs75332508

2

76156698

T/C

T

0.041

intergenic

0.17

0.14

0.070

-

CA153

MUC1

rs4072037

1

155192276

C/T

C

0.176

exonic

-2.78

0.92

3.73E-08*

2.31E-06*

LOC100128317

rs12113394

7

81597863

G/A

G

0.226

ncRNA_intronic

-2.24

0.95

0.776

-

  1. CA125 Carbohydrate Antigen CA125, CA153 Carbohydrate Antigen CA153, MA Minor allele, MAF Minor allele frequency, FDR False Discovery Rate
  2. ‘-’ indicates the insignificant results
  3. p-value indicates the level of significant association.
  4. p < 0.05 indicates that candidate SNP is significantly associated with the tumor maker in participants