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Table 3 Univariate and multivariate analyses with respect to RFS in postmenopausal HR-positive/HER2-negative breast cancer treated for dyslipidemia

From: Relationship between serum lipid levels and the immune microenvironment in breast cancer patients: a retrospective study

 

Univariate analysis

Multivariate analysis

Hazard ratio

95% CI

p-value

Hazard ratio

95% CI

p-value

Age at diagnosis (>65)

1.034

0.324-3.882

0.957

   

BMI (>25.1)

1.383

0.423-4.548

0.584

   

Diabetes (negative)

1.348

0.398-6.115

0.649

   

Adjuvant chemotherapy (-)

1.196

0.264-4.044

0.793

   

Serum lipid level (preoperative) (Low, normal)

1.204

0.376-3.852

0.748

   

Tumor size (>2)

2.010

0.640-6.803

0.230

   

Lymph node (+)

1.862

0.549-5.854

0.302

   

NLR (preoperative) (High)

2.595

0.684-16.898

0.175

   

NLR (postoperative) (High)

2.573×109

2.868-unparsable

0.002

2.087×109

2.367-unparsable

0.992

Serum lipid control (Poor)

5.534

1.448-36.136

0.010

4.722

1.006-22.161

0.049

TILs (High)

2.229

0.608-8.153

0.218

   
  1. Values in parentheses are 95 per cent confidence intervals
  2. CI confidence interval, BMI body mass index, NLR neutrophil-to-lymphocyte ratio, TILs tumor-infiltrating lymphocyte