Table 2 Summary of time points of the translational program. h = hour
ICG fluorescence | Biomarkers | |
|---|---|---|
< 24 h to start of ISCON | Biopsies of anastomotic site + peripheral blood (10 ml EDTA) | |
ISCON: before occlusion of arteries | X | |
ISCON: 10 min after occlusion of arteries | X | |
< 24 h to start of esophagectomy | Biopsies of anastomotic site + peripheral blood (10 ml EDTA) | |
Esophagectomy: before formation of gastric tube | X | |
Optional: esophagectomy: before formation of intrathoracic anastomosis | (X) | |
Esophagectomy: after completion of anastomosis | Gastric anastomotic donut or tip of gastric tube |