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Table 2 Univariate and multivariate Cox regression analysis of clinical pathologic features for OS in TCGA

From: Natural killer cell-related gene signature predicts malignancy of glioma and the survival of patients

 

TCGA cohort

Univariate analysis

Multivariate analysis

Characteristics

P-value

HR

95% CI

P-value

HR

95% CI

Age

< 0.001

1.073

1.061–1.084

< 0.001

1.066

1.049–1.084

Gender

0.462

0.9

0.681–1.191

0.68

1.08

0.749–1.559

Grade

< 0.001

3.093

2.637–3.628

0.028

1.33

1.032–1.714

Subtype

< 0.001

2.004

1.765–2.275

0.11

1.194

0.961–1.484

IDH

< 0.001

8.561

6.228–11.768

0.17

1.616

0.814–3.21

MGMT promoter

< 0.001

0.228

0.139–0.376

0.026

0.508

0.28–0.921

1p/19q

< 0.001

2.964

2.17–4.047

0.5

1.165

0.748–1.816

Risk score

< 0.001

1.126

1.099–1.154

0.007

1.066

1.018–1.117