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Fig. 2 | BMC Cancer

Fig. 2

From: Improving power in PSA response analyses of metastatic castration-resistant prostate cancer trials

Fig. 2

Comparison of the standard and augmented analysis approaches for the 78 included mCRPC datasets. Points are shaded according to the value of the standard point estimate. A: The standard and augmented point estimated are compared. B: The width of the standard and augmented point estimates are compared. C: The efficiency gains, in terms of the percentage confidence interval width reduction, are given. D: The efficiency gains, in terms of the percentage increase to the trial’s sample size, are given. For D, the limits are constrained to [0,500] for aesthetic purposes; 9 trials for which substantially larger efficiency gains were observed are omitted from this sub-figure

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