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Table 2 Comparison of Preoperative Risk Factors for Postoperative Death Within 1 Year After Tumor Recurrence

From: Online calculator to predict early mortality in patient with surgically treated recurrent lower-grade glioma

Characteristics

Death Within 1 Year (23)

Death After 1 Year (83)

P value

Age, years

 Average

41.83

39.61

0.618

 Range

24–68

18–70

 

Gender, n (%)

 Female

5 (21.7%)

27 (32.5%)

0.233

 Male

18 (78.2%)

56 (67.5%)

 

Location, n (%)

 Frontal

8 (34.8%)

30 (37.3%)

0.953

 Temporal

4 (17.4%)

17 (20.5%)

 

 Multi

6 (26.1%)

22 (26.5%)

 

 Other

5 (21.7%)

14 (15.7%)

 

Initial symptom, n (%)

 Epilepsy

17 (73.9%)

39 (47.0%)

0.019

 Other

6 (26.1%)

44 (53.0%)

 

First diagnosed grade, n (%)

 WHO II

16 (69.6%)

61 (73.5%)

0.447

 WHO III

7 (30.4%)

22 (26.5%)

 

First diagnosed pathology type, n (%)

 Astrocytoma

16 (69.6%)

46 (55.4%)

0.164

 Oligodendroglial

7 (30.4%)

37 (44.6%)

 

Malignant transform, n (%)

 Yes

8 (34.8%)

25 (30.1%)

0.425

 No

15 (65.2%)

58 (69.9%)

 

P53, n (%)

 Mutant

19 (82.6%)

58 (69.9%)

0.172

 Wide

4 (17.4%)

25 (30.1%)

 

1p/19q Codeletion, n (%)

 yes

6 (26.1%)

41 (49.4%)

0.038

 No

17 (73.9%)

42 (50.6%)

 

IDH1, n (%)

 Mutant

15 (65.2%)

58 (69.9%)

0.425

 Wide

8 (34.8%)

25 (30.1%)

 

ATRX, n (%)

 Mutant

15 (65.2%)

51 (61.4%)

0.470

 Wide

8 (34.8%)

32 (38.6%)

 

Ki-67, n

 Average

16.13

17.95

0.870

 Range

2–80

0–70

 

Adjuvant therapy, n (%)

 Stupp

10 (43.5%)

58 (69.9%)

0.019

 Other

13 (56.5%)

25 (30.1%)

 

NLR, n (%)

 ≤1.815

4 (17.4%)

32 (38.6%)

0.046

 >1.815

19 (82.6%)

51 (61.4%)

 

PLR, n (%)

 ≤100.749

4 (17.4%)

36 (43.4%)

0.018

 >100.749

19 (82.6%)

47 (56.6%)

 

LMR, n (%)

 ≤3.029

6 (26.1%)

27 (32.5%)

0.375

 >3.029

17 (73.9%)

56 (67.5%)

 

RDW, n% (%)

 ≤13.4

11 (47.8%)

59 (71.1%)

0.035

 >13.4

12 (52.2%)

24 (28.9%)

 

Fib, g/L, n (%)

 ≤2.80

10 (43.5%)

58 (69.9%)

0.019

 >2.80

13 (56.5%)

25 (30.1%)

 

DD, mg/L, n (%)

 ≤0.187

11 (47.8%)

61 (73.5%)

0.020

 >0.187

12 (52.2%)

22 (26.5%)

 

TTR, days

 Average

1777.48

1814.64

0.908

 Range

216–5425

177–6310

 
  1. IDH1 isocitrate dehydrogenase 1, ATRX alpha thalassemia/mental retardation syndrome X-linked, NLR the neutrophil-to-lymphocyte ratio, PLR the platelet-to-lymphocyte ratio, LMR the lymphocyte-to-monocyte ratio, RDW red blood cell distribution width, FIB fibrinogen, DD D-dimer, IQR interquartile range, TTR time to recurrence, OS overall survival