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Table 1 Summary of Clinical Characteristics of LGG Patients Who Undergo Recurrence

From: Online calculator to predict early mortality in patient with surgically treated recurrent lower-grade glioma

Characteristic

All Patients, N = 106

Age, years

 Average

40.09

 Range

18–70

Gender, n (%)

 Female

32 (30.2%)

 Male

74 (69.8%)

Location, n (%)

 Frontal

38 (35.9%)

 Temporal

21 (19.8%)

 Multi

28 (26.4%)

 Other

19 (17.9%)

Initial symptom, n (%)

 Epilepsy

56 (52.8%)

 Other

50 (47.2%)

First diagnosed grade, n (%)

 WHO II

77 (72.6%)

 WHO III

29 (27.4%)

First diagnosed pathology type, n (%)

 Astrocytoma

62 (58.5%)

 Oligodendroglial

44 (41.5%)

Malignant transform, n (%)

 Yes

33 (31.1%)

 No

73 (68.9%)

P53, n (%)

 Mutant

77 (72.6%)

 Wide

29 (27.4%)

1p/19q Codeletion, n (%)

 Yes

47 (44.3%)

 No

59 (55.7%)

IDH1-R132H, n (%)

 Mutant

73 (68.9%)

 Wide

33 (31.1%)

ATRX, n (%)

 Mutant

66 (62.3%)

 Wide

40 (37.7%)

Ki-67, n

 Average

17.04

 Range

0–80

Adjuvant therapy, n (%)

 Stupp

68 (64.2%)

 Other

38 (35.8%)

Blood work, average (IQR)

 NLR,

2.820 (0.667–21.298)

 PLR,

128.653 (41.026–578.723)

 LMR,

4.191 (0.181–21.667)

 RDW, %

13.65 (12.0–23.6)

 FIB, g/L

2.74 (1.26–14.30)

 DD, mg/L

0.160 (0.005–1.080)

TTR, days

 

 Average

1806.58

 Range

177–6310

PRS, days

 

 Average

768.86

 Range

39–1981

OS, days

 

 Average

2575.43

 Range

263–8176

Survival Status, n (%)

 

 Alive

42 (39.6%)

 Dead

64 (60.4%)

  1. IDH1 Isocitrate dehydrogenase 1, ATRX Alpha thalassemia/mental retardation syndrome X-linked, NLR the neutrophil-to-lymphocyte ratio, PLR the platelet-to-lymphocyte ratio, LMR the lymphocyte-to-monocyte ratio, RDW Red blood cell distribution width, FIB fibrinogen, DD D-dimer, IQR Interquartile range, TTR Time to recurrence, PRS Post recurrence survival, OS Overall survival