Skip to main content

Table 4 Univariate and multivariate Cox proportional hazards model analysis for overall survival

From: Predictive value of preoperative platelet-to-albumin ratio and apolipoprotein B-to-apolipoprotein A1 ratio for osteosarcoma in children and adolescents: a retrospective study of 118 cases

Characteristics

Univariate analysis

Multivariate analysis

HR

95%CI

P value

HR

95%CI

P value

Age (years)

  

0.299

   

  ≤ 16

1.000

Reference

    

  > 16

1.358

0.762–2.420

    

Gender

  

0.910

   

 Male

1.000

Reference

    

 Female

0.983

0.734–1.317

    

Tumor size (cm)

  

0.017

  

0.349

  ≤ 5

1.000

Reference

 

1.000

Reference

 

  > 5

2.006

1.130–3.563

 

1.408

0.688–2.883

 

Tumor site

  

0.946

   

 Extremities

1.000

Reference

    

 Non-extremities

0.979

0.525–1.824

    

Histological type

  

0.415

   

 Well-differentiated

1.000

Reference

    

 Poorly differentiated

1.272

0.714–2.266

    

Enneking stage

  

 < 0.001

  

0.007

 I/II

1.000

Reference

 

1.000

Reference

 

 III

5.695

2.910–11.147

 

3.213

1.373–7.520

 

Pathological fracture

  

 < 0.001

  

0.162

 Yes

1.000

Reference

 

1.000

Reference

 

 No

0.267

0.144–0.494

 

0.589

0.281–1.236

 

Neoadjuvant chemotherapy

  

0.329

   

 Yes

1.000

Reference

    

 No

1.331

0.749–2.365

    

Local recurrence

  

0.001

  

0.029

 Yes

1.000

Reference

 

1.000

Reference

 

 No

0.384

0.213–0.693

 

0.420

0.193–0.917

 

Metastasis

  

 < 0.001

  

 < 0.001

 Yes

1.000

Reference

 

1.000

Reference

 

 No

0.286

0.158–0.516

 

0.252

0.123–0.518

 

PAR

  

 < 0.001

  

0.033

 High

1.000

Reference

 

1.000

Reference

 

 Low

0.274

0.141–0.533

 

0.428

0.196–0.934

 

PLR

  

0.019

  

0.438

 High

1.000

Reference

 

1.000

Reference

 

 Low

0.494

0.274–0.892

 

0.766

0.390–1.504

 

LDL-C/HDL-C

  

0.033

  

0.115

 High

1.000

Reference

 

1.000

Reference

 

 Low

0.535

0.302–0.950

 

0.572

0.285–1.145

 

ApoB/ApoA1

  

 < 0.001

  

0.001

 High

1.000

Reference

 

1.000

Reference

 

 Low

0.336

0.186–0.606

 

0.268

0.135–0.530

 
  1. Data were analyzed by Cox proportional hazards model. P < 0.05 was considered significant
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us