Predictive value of preoperative platelet-to-albumin ratio and apolipoprotein B-to-apolipoprotein A1 ratio for osteosarcoma in children and adolescents: a retrospective study of 118 cases

Table 2 Identification of optimal cut-off values for different prognostic factors based on the ROC curve

Factor	Optimal cut-off value	Sensitivity	Specificity	Youden index	Positive predictive value	Negative predictive value	Overall accuracy rate	AUC	95% CI	P value
PAR	4.41	0.745	0.620	0.365	0.565	0.786	0.669	0.686	0.591–0.781	0.001
PLR	209.54	0.393	0.803	0.196	0.563	0.663	0.636	0.593	0.477–0.690	0.036
LDL-C/HDL-C	2.04	0.511	0.704	0.215	0.533	0.685	0.627	0.606	0.493–0.700	0.017
ApoB/ApoA1	0.82	0.723	0.582	0.305	0.630	0.641	0.636	0.699	0.603–0.796	< 0.001

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