Fig. 6
From: Integrated analysis of the prognostic and oncogenic roles of OPN3 in human cancers
Gene set enrichment analysis of OPN3 in five types of cancer. The intersection of OPN3 and the top 500 OPN3-associated genes (A, positive correlation of genes; B, negative correlation of genes) in each cancer type. The GO (C) and KEGG (D) pathways that were enriched by the top ranked genes in the low and high OPN3 expression groups were detected by GSEA. For each analysis, the number of gene set permutations was set to 1000. The nominal (NOM) P value, false discovery rate (FDR < 0.25) and normalized enrichment score (NES) were used to identify the pathways enriched in each phenotype