Table 4 Comparative results of genotypic frequencies of selected polymorphisms in cases and controls and the association with glioblastoma risk. Significant P-values are represented in bold
From: Polymorphisms in autophagy genes are genetic susceptibility factors in glioblastoma development
SNP | Allele | Cases N (%) | Controls N (%) | p-value | OR (IC 95%) |
|---|---|---|---|---|---|
ATG2B rs3759601 | C | 183 (52.6%) | 193 (36.6%) | 0.000 | 1 |
G | 165 (47.4%) | 335 (63.4%) | / | 0.519 (0.395–0.684) | |
ATG5 rs2245214 | C | 219 (62.9%) | 339 (64.2%) | 0.720 | |
G | 129 (37.1%) | 189 (35.8%) | / | ||
ATG10 rs1864183 | C | 160 (46%) | 287 (54.4%) | 0.016 | 1 |
T | 188 (54%) | 241 (45.6%) | / | 0.399 (1.066–1.836) | |
ATG16L1 rs2241880 | G | 128 (52.3%) | 264(50%) | 0.505 | |
A | 166 (47.7%) | 264 (50%) | / | ||
NOD2 rs2066844 | C | 305 (87.6%) | 355 (93.9%) | 0.003 | 1 |
T | 43 (12.4%) | 23 (6.1%) | / | 2.173 (1.282–3.693) | |
NOD2 rs2066845 | G | 342 (98.3%) | 201 (99.5%) | 0.21 | |
C | 6 (1.7%) | 1 (0.5%) | / |