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Table 3 Relationship between TSP2 expression and clinicopathological characteristics in 80 cases of gastric cancer (n%)

From: Thrombospondin-2 holds prognostic value and is associated with metastasis and the mismatch repair process in gastric cancer

Clinical

Cases

TSP2 expression

χ2

P-value

characteristics

 

Low

High

  

Age (years)

   

1.802

0.180

 <65

34

12(35.3)

22(64.7)

 ≥65

46

10(21.7)

36(78.3)

Gender

   

1.863

0.172

 Male

41

14(34.1)

27(65.9)

 Female

39

8 (20.5)

31(79.5)

TNM stage

   

12.406

<0.01

 I/II

33

16(48.5)

17(51.5)

 III/IV

47

6 (12.8)

41(87.2)

T stage

   

2.190

0.139

 T1/T2

23

9 (39.1)

14(60.9)

 T3/T4

57

13(22.8)

44(77.2)

N stage

   

4.296

0.038

 N0

33

5 (15.2)

28(84.8)

 N(1 + 2 + 3)

47

17(36.2)

30(63.8)

M stage

   

5.035

0.025

 M0

68

15(22.1)

53(77.9)

 M1

12

7 (58.3)

5 (41.7)

Differentiation

   

0.348

0.555

Poor/undifferentiated

43

13(30.2)

30(69.8)

 Well/moderate

37

9 (24.3)

28(75.7)

MSI/MMR

   

16.425

<0.01

 pMMR/ MSI-L/MSS

66

12(18.2)

54(81.8)

 dMMR/MSI-H

14

10(71.4)

4 (28.6)

  1. Abbreviations: pMMR proficient mismatch repair, MSI-L microsatellite instability low, MSS microsatellite stable, dMMR deficient mismatch repair, MSI-H microsatellite instability high