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Table 3 Relationship between TSP2 expression and clinicopathological characteristics in 80 cases of gastric cancer (n%)

From: Thrombospondin-2 holds prognostic value and is associated with metastasis and the mismatch repair process in gastric cancer

Clinical Cases TSP2 expression χ2 P-value
characteristics   Low High   
Age (years)     1.802 0.180
 <65 34 12(35.3) 22(64.7)
 ≥65 46 10(21.7) 36(78.3)
Gender     1.863 0.172
 Male 41 14(34.1) 27(65.9)
 Female 39 8 (20.5) 31(79.5)
TNM stage     12.406 <0.01
 I/II 33 16(48.5) 17(51.5)
 III/IV 47 6 (12.8) 41(87.2)
T stage     2.190 0.139
 T1/T2 23 9 (39.1) 14(60.9)
 T3/T4 57 13(22.8) 44(77.2)
N stage     4.296 0.038
 N0 33 5 (15.2) 28(84.8)
 N(1 + 2 + 3) 47 17(36.2) 30(63.8)
M stage     5.035 0.025
 M0 68 15(22.1) 53(77.9)
 M1 12 7 (58.3) 5 (41.7)
Differentiation     0.348 0.555
Poor/undifferentiated 43 13(30.2) 30(69.8)
 Well/moderate 37 9 (24.3) 28(75.7)
MSI/MMR     16.425 <0.01
 pMMR/ MSI-L/MSS 66 12(18.2) 54(81.8)
 dMMR/MSI-H 14 10(71.4) 4 (28.6)
  1. Abbreviations: pMMR proficient mismatch repair, MSI-L microsatellite instability low, MSS microsatellite stable, dMMR deficient mismatch repair, MSI-H microsatellite instability high