Table 1 The effect of TSP2 in the Kaplan-Meier Plotter database on the prognosis of patients with different subgroups of GC

Gender

Female

236

2.05 (1.44–2.92)

4.9e−05

Male

545

1.52 (1.22–1.89)

0.00015

Treatment

Surgery alone

380

1.71 (1.28–2.29)

0.00023

5 FU based

153

0.65 (0.46–0.92)

0.014

Other adjuvant

76

2.82(1.17–6.79)

0.015

HER2 status

Negative

532

1.58(1.25–1.99)

9.4e−05

Positive

344

1.58 (1.22–2.05)

0.00049

Stage

StageI

67

0.45 (0.17–1.24)

0.11

StageII

140

0.62(1.34–1.14)

0.12

StageIII

305

1.89(1.41–2.53)

1.4e−05

StageIV

148

1.87(1.27–2.77)

0.0014

Stage T

T2

241

1.84(1.18–2.86)

0.0061

T3

204

1.87(1.32–2.63)

3.0e−04

T4

38

1.91(0.82–4.47)

0.13

Stage N

N0

74

1.67(0.73–3.83)

0.22

N (1 + 2 + 3)

422

2.36(1.81–3.09)

8.2e−11

N1

225

2.31(1.53–3.48)

3.8e−05

N2

121

2.92(1.84–4.63)

1.9e-6

N3

76

2.27(1.31–3.91)

0.0026

Stage M

M0

444

2.14(1.62–2.83)

3.9e-8

M1

56

1.84(1.01–3.33)

0.042

Lauren classification

Instestinal

320

2.49 (1.8–3.46)

1.6e-8

Diffuse

241

1.89 (1.34–2.66)

0.00023

Differentiation

Mixed

33

4.55 (1.56–13.32)

0.0025

Poorly

165

1.79 (1.16–2.75)

0.0074

Moderately

67

2.71 (1.35–5.44)

0.0036

Well

32

4.36 (1.8–10.54)

4.0e-04