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Table 1 The effect of TSP2 in the Kaplan-Meier Plotter database on the prognosis of patients with different subgroups of GC

From: Thrombospondin-2 holds prognostic value and is associated with metastasis and the mismatch repair process in gastric cancer

Clinical characteristics Items Cases HR (95% CI) P value
Gender Female 236 2.05 (1.44–2.92) 4.9e−05
Male 545 1.52 (1.22–1.89) 0.00015
Treatment Surgery alone 380 1.71 (1.28–2.29) 0.00023
5 FU based 153 0.65 (0.46–0.92) 0.014
Other adjuvant 76 2.82(1.17–6.79) 0.015
HER2 status Negative 532 1.58(1.25–1.99) 9.4e−05
Positive 344 1.58 (1.22–2.05) 0.00049
Stage StageI 67 0.45 (0.17–1.24) 0.11
StageII 140 0.62(1.34–1.14) 0.12
StageIII 305 1.89(1.41–2.53) 1.4e−05
StageIV 148 1.87(1.27–2.77) 0.0014
Stage T T2 241 1.84(1.18–2.86) 0.0061
T3 204 1.87(1.32–2.63) 3.0e−04
T4 38 1.91(0.82–4.47) 0.13
Stage N N0 74 1.67(0.73–3.83) 0.22
N (1 + 2 + 3) 422 2.36(1.81–3.09) 8.2e−11
N1 225 2.31(1.53–3.48) 3.8e−05
N2 121 2.92(1.84–4.63) 1.9e-6
N3 76 2.27(1.31–3.91) 0.0026
Stage M M0 444 2.14(1.62–2.83) 3.9e-8
M1 56 1.84(1.01–3.33) 0.042
Lauren classification Instestinal 320 2.49 (1.8–3.46) 1.6e-8
Diffuse 241 1.89 (1.34–2.66) 0.00023
Differentiation Mixed 33 4.55 (1.56–13.32) 0.0025
Poorly 165 1.79 (1.16–2.75) 0.0074
Moderately 67 2.71 (1.35–5.44) 0.0036
Well 32 4.36 (1.8–10.54) 4.0e-04