Table 1 Baseline demographic and clinicopathological characteristics stratified using the tumour size ratio
Variables | Number of Patients | Tumour Size Ratio | P-value | ||
|---|---|---|---|---|---|
< 2 (n = 41) | ≥ 2– < 4 (n = 70) | ≥ 4 (n = 36) | |||
Age (years) | |||||
≤ 60 | 80 (54.4) | 20 (48.8) | 40 (57.1) | 20 (55.6) | 0.686 |
˃60 | 67 (45.6) | 21 (51.2) | 30 (42.9) | 16 (44.4) | |
Sex | |||||
male | 90 (61.2) | 26 (63.4) | 42 (60.0) | 22 (61.1) | 0.938 |
female | 57 (38.8) | 15 (36.6) | 28 (40.0) | 14 (38.9) | |
Primary Tumour Location | |||||
Colon | 69 (46.9) | 23 (56.1) | 28 (40.0) | 18 (50.0) | 0.238 |
Rectum | 78 (53.1) | 18 (43.9) | 42 (60.0) | 18 (50.0) | |
T category | |||||
T1–T3 | 72 (49.0) | 18 (43.9) | 30 (43.5) | 24 (66.7) | 0.067 |
T4 | 72 (49.0) | 21 (51.2) | 39 (55.7) | 12 (33.3) | |
Missing | 3 (2.0) | 2 (4.9) | 1 (1.4) | - | |
N category | |||||
N0 + N1 | 107 (72.8) | 28 (68.3) | 46 (65.7) | 33 (91.7) | 0.019 |
N2 | 37 (25.2) | 11 (26.8) | 23 (32.9) | 3 (8.3) | |
Missing | 3 (2.0) | 2 (4.9) | 1 (1.4) | - | |
Primary Tumour Differentiation | |||||
Well + Moderate | 90 (61.2) | 29 (70.7) | 38 (54.3) | 23 (63.9) | 0.219 |
Poor + Others | 47 (32.0) | 9 (22.0) | 26 (37.1) | 12 (33.3) | |
Missing | 10 (6.8) | 3 (7.3) | 6 (8.6) | 1 (2.8) | |
Preoperative CEA (ng/mL) | |||||
≤ 200 | 124 (84.4) | 33 (80.5) | 63 (90.0) | 28 (77.8) | 0.142 |
˃200 | 21 (14.3) | 7 (17.1) | 6 (8.6) | 8 (22.2) | |
Missing | 2 (1.4) | 1 (2.4) | 1 (1.4) | - | |
Extrahepatic Disease | |||||
No | 120 (81.6) | 35 (85.4) | 58 (82.9) | 27 (75.0) | 0.471 |
Yes | 27 (18.4) | 6 (14.6) | 12 (17.1) | 9 (25.0) | |
Presentation | |||||
Synchronous CRLM | 98 (66.7) | 27 (65.9) | 50 (71.4) | 21 (58.3) | 0.396 |
Metachronous CRLM | 49 (33.3) | 14 (34.1) | 20 (28.6) | 15 (41.7) | |
Size of the Largest CRLM, Median (IQR) | 3.0 (2.0–4.0) | 3.0 (1.5–4.2) | 2.5 (1.5–3.5) | 4.0 (2.8–6.0) | 0.001 |
Number of CRLMs, Median (IQR) | 3.0 (2.0–5.0) | 2.0 (2.0–3.0) | 3.0 (2.0–5.0) | 4.0 (3.0–5.7) | 0.005 |
Location on the Liver | |||||
Unilobar Disease | 54 (36.7) | 20 (48.8) | 22 (31.4) | 12 (33.3) | 0.166 |
Bilobar Disease | 93 (63.3) | 21 (51.2) | 48 (68.6) | 24 (66.7) | |
Type of Surgical Procedure | |||||
Resection | 109 (74.1) | 35 (85.4) | 49 (70.0) | 25 (69.4) | 0.154 |
Resection + Ablation | 38 (25.9) | 6 (14.6) | 21 (30.0) | 11 (30.6) | |