Table 1 Characteristics of the included studies
From: Prognostic significance of KLF4 in solid tumours: an updated meta-analysis
Author, year | No.(M/F) | Tumor Location | Method | Stage | KLF4 +/− | Region | Anasysis | OS | DFS |
|---|---|---|---|---|---|---|---|---|---|
Hazard ratio | Hazard ratio | ||||||||
Zhen Liu 2013 [27] | 165(112/53) | NPC | IHC | I-IV | 63/102 | China | OS | 0.25 | Â |
Hongcheng Sun 2016Â [23] | 98(84/14) | HCC | IHC | I-III | NR | USA | OS/DFS | 4.59 | 5.42 |
Qi Li 2012Â [24] | 40 (NR) | HCC | IHC | Â | NR | China | OS | 30.74 | Â |
Hui-Ting Hsu 2014 [37] | 205(121/84) | HCC | IHC | I-IV | 45/160 | China(Taipei) | DFS | Â | 0.398 |
Xin Yin 2013 [19] | 57(48/9) | HCC | PCR | I-III | 7/50 | China | OS/DFS | 5.08 | 2.88 |
H Sun 2017 [30] | 148(129/19) | HCC | IHC | I-III | 81/67 | China | OS/DFS | 0.29 | 0.29 |
Heng Li 2013 [41] | 149(106/43) | RCC | IHC | I-IV | 103/46 | China | OS/DFS | 0.65 | 0.48 |
Heng Li 2014 [39] | 139(102/37) | UCB | IHC | Ta-T1 | 56/83 | China | RFS |  | 0.51 |
Wei-Cheng Tseng 2016 [25] | 227(146/81) | UCB | IHC | Ta-T4 | 73/154 | China(Taipei) | OS | 1.39 |  |
Shyh-Kuan Tai 2011 [31] | 62(58/4) | HNSCC | IHC | I-IV | 20/42 | China(Taipei) | DSS |  | 2.13 |
Nilesh Patel 2010 [20] | 365(192/173) | colon cancer | IHC | I-IV | 249/106 | USA | OS/DFS | 0.87 | 0.62 |
Ha-young Lee 2014 [36] | 125 (82/43) | CRC | PCR | I-IV | 45/80 | South Korea | OS | 2.6 |  |
Jing Xu 2008 [38] | 60 (NR) | CRC | IHC | NR | 18/42 | China | OS | 1.03 |  |
WÂ Tang 2014 [29] | 85(46/39) | CRC | PCR | I-IV | 43/42 | China | OS | 0.56 | Â |
Ming-Quan Ma 2014 [34] | 98(64/34) | ESCC | IHC | I-III | 43/55 | China | OS | 0.79 |  |
Yutaka Shimada 2012 [28] | 80 (71/9) | ESCC | IHC | I-IV | 30/50 | Japan | DSS | 0.79 |  |
Chang Yuan 2016 [22] | 126(0/126) | BC | IHC | I-III | 61/65 | China | OS/DFS | 0.67 | 0.53 |
Takuya Nagata 2016 [13] | 208(0/208) | TNBC | IHC | I-III | 100/108 | Japan | OS/DFS | 0.56 | 0.69 |
Takuya Nagata 2012 [15] | 100(0/100) | BC | IHC | I-III | 44/56 | Japan | OS/DFS | 0.318 | 0.256 |
Ashka Y 2004 [10] | 146 (0/146) | BC | IHC | I-IV | 114/32 | Britain | OS | 0.46 | Â |
Li-Sung Hsu 2013 [35] | 118(82/36) | GC | IHC | I-IV | 87/31 | China | OS | 0.65 |  |
Daoyan Wei 2005 [43] | 39(27/12) | GC | IHC | I-IV | 12/27 | USA | OS | 2.18 | Â |
Isaya Hashimoto 2017 [40] | 108(77/31) | GC | IHC | I-IV | 72/36 | Japan | OS | 0.57 |  |
Niccola Funel 2011 [33] | 22 (NR) | PDAC | PCR | NR | 6/16 | Italy | OS/DFS | 2.5 | 2.6 |
Zhulin Yang 2016 [26] | 106(61/45) | PDAC | IHC | I-IV | 47/59 | China | OS | 0.38 | Â |
Daoyan Wei 2010 [21] | 22(NR) | PDAC | IHC | II | 4/18 | USA | OS | 2.01 |  |
Hai-Xia Liu 2017 [42] | 117(0/117) | LACSCC | IHC | II-IV | 53/64 | China | OS/PFS | 1.29 | 2.55 |
Rumi Yoshihama 2016 [32] | 108(69/39) | OSCC | IHC | T1-T4 | 53/55 | Japan | OS/DFS | 1.17 | 1.65 |
Chih-Jung Chen 2011 [44] | 215(205/10) | OSCC | IHC | I-IV | 191/24 | China(Taiwan) | OS | 0.46 |  |
Alberto Valencia-Hipólito 2014 [45] | 73(46/27) | NHL | IHC | I-IV | 48/25 | Mexico | OS | 1.84 |  |