Table 4 The most remarkably enriched signaling pathways of differentially expressed genes

hsa04110

Cell cycle

39

4.93E-09

E2F1, E2F3, CDC14A, TTK, PRKDC, PTTG2, CHEK1, CHEK2, CCNE1, CDC45, MCM7, TFDP2, BUB1, ORC5, ORC6, CCNA2, MYC, TFDP1, ANAPC1, CDK1, RBL1, SKP2, ESPL1, CDC20, MCM2, CDK4, CDC25C, MCM3, MCM4, CDK2, MCM6, CDC25B, CCNB1, CCND1, HDAC2, CCNB2, MAD2L1, PLK1, BUB1B

6.54E-06

hsa03030

DNA replication

19

1.10E-08

SSBP1, LIG1, POLA1, MCM2, RNASEH2A, MCM3, MCM4, RNASEH2B, MCM6, PRIM1, POLD4, RFC3, RFC4, MCM7, RFC2, POLD1, PRIM2, POLD2, FEN1

1.46E-05

hsa00230

Purine metabolism

40

2.78E-05

ADCY3, XDH, ADCY5, PNPT1, POLA1, POLR2D, HPRT1, PPAT, CANT1, PDE6A, PRIM1, NUDT9, ENTPD8, PRIM2, ENTPD5, ENTPD3, PDE8A, PRPS1L1, TWISTNB, IMPDH1, PAPSS2, NUDT16, ADSSL1, POLR1E, POLR1D, PDE3A, POLR1B, AMPD2, GMPS, GART, AMPD1, POLD4, PDE7B, ADCY9, ADK, POLD1, POLD2, PDE5A, PGM1, PAICS

0.036956