Fig. 5
From: Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma
PFKFB3 knockdown inhibits RCC tumor growth in murine models. (a) Imaging of ACHN cell-based cancer formation in murines under different conditions. (b) Statistics for ACHN cell-based tumor volumes in nude murines (n = 6 per group). (c) Statistics for ACHN cell-based tumor weight in nude murines (n = 6 per group). (d) PFKFB3 mRNA levels were detected in tumors from different groups. (e) IHC imaging of PFKFB3 and Ki-67 in randomized ACHN cancer cells. (f) Quantification of IHC staining of Ki-67 in ACHN cell-based tumors. The results are presented as the mean ± SD. *, P < 0.05; **, P < 0.01