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Table 1 Patient Characteristics

From: Routine use of low-dose glucarpidase following high-dose methotrexate in adult patients with CNS lymphoma: an open-label, multi-center phase I study

Sex, No. (%)
Men 6 (75%)
Women 2 (25%)
Median age, years (range) 70 (57–78)
KPS, (range) 70 (50–100)
Location, No. (%)  
Primary 7 (87.5%)
Secondary 1 (12.5%)
Disease Status
Newly diagnosed 7 (87.5%)
Recurrent 1 (12.5%)
Leptomeningeal disease 3 (37.5%)
Ocular disease 0 (0%)
Median Prior Regimens, No. (range) 0 (0–3)
MTX 3 g/m2(patients) 4
Glucarpidase 2000u 17 doses
Glucarpidase 1000u 11 doses
MTX 6 g/m2(patients) 4
Glucarpidase 2000u 18 doses
Glucarpidase 1000u 9 doses