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Table 2 Univariate and multiple regression analysis for changes of lower limb circumference

From: Factors associated with response to compression-based physical therapy for secondary lower limb lymphedema after gynecologic cancer treatment: a multicenter retrospective study

   Early phase Maintenance phase
   Univariate analysis Multivariate regression analysis Univariate analysis Multivariate regression analysis
Characteristics Categories   P value Standardized Coefficient P value   P value Standardized Coefficient P value
Age, CCa    − 0.073 0.061  − 0.111 0.007  − 0.098 0.010  − 0.134  < 0.001
BMI, CCa    − 0.299  < 0.001 0.447  < 0.001  − 0.348  < 0.001 0.456  < 0.001
Type of cancer, cm (SD)b Cervical cancer  − 7.20 (7.53) 0.268 referent    − 9.65 (9.64) 0.008 referent  
Endometrial cancer  − 6.26 (7.01)   0.034 0.444  − 7.40 (9.64)   0.087 0.037
Ovarian cancer  − 6.27 (7.37)   0.014 0.755  − 7.28 (8.81)   0.029 0.484
Lymphadenectomy, cm (SD)b Pelvic  − 4.45 (9.90) 0.014 referent    − 8.46 (12.05)  < 0.001 referent  
Pelvic + paraaorta  − 6.57 (8.17)    − 0.022 0.596  − 4.78 (9.29)    − 0.055 0.132
Chemotherapy, cm (SD)b Yes  − 2.88 (10.66) 0.002 0.011 0.825  − 1.75 (11.24)  < 0.001  − 0.010 0.140
No  − 6.88 (9.24)      − 8.29 (8.28)    
Radiotherapy, cm (SD)b Yes  − 7.28 (12.29) 0.242 0.108 0.012  − 9.11 (14.53) 0.074 0.082 0.040
No  − 6.35 (8.22)      − 7.16 (9.65)    
Stage, cm (SD)b I  − 1.53 (5.32)  < 0.001 referent    − 0.13 (4.66)  < 0.001 referent  
II  − 5.81 (7.61)   0.044 0.704  − 6.97 (9.32)    − 0.168 0.141
Late in II  − 9.61 (10.57)   0.053 0.640  − 11.96 (12.65)    − 0.093 0.407
III  − 27.32 (31.34)   0.01 0.849  − 31.76 (38.43)    − 0.056 0.260
Circumference, CCa    − 0.608  < 0.001  − 0.828  < 0.001  − 0.671  < 0.001  − 0.920  < 0.001
MLD, cm (SD)b Yes  − 6.54 (9.35) 0.768 0.013 0.794  − 8.17 (11.52) 0.012 0.011 0.796
No  − 6.87 (9.40)      − 5.40 (8.60)    
  1. Statistically significant results are marked in bold
  2. BMI Body mass index, MLD Manual lymphatic drainage
  3. aData are expressed as a correlation coefficient (CC)
  4. bData are expressed as the group mean (standard deviation [SD])