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Table 4 The multivariate logistic regression analysis of risk factors for positive HM en bloc resected by HSP, EMR or ESD

From: Influence of early colorectal cancer component on the positive margins after endoscopic resection: a retrospective study

 

Positive HM

HSP

EMR

ESD

OR

95%CI

P

OR

95%CI

P

OR

95%CI

P

Size

  ≤ 1 cm

Ref

  

Ref

  

Ref

  

  ≤ 2 cm

2.12

0.04–125.82

0.719

1.27

0.34–4.77

0.719

0.52

1.000

  > 2 cm

0.00

0.998

0.00

0.993

0.00

0.998

Morphology

 Sessile

Ref

  

Ref

  

Ref

  

 Pedunculated

0.16

0.00–7.89

0.36

0.53

0.15–1.91

0.331

0.68

0.07–6.92

0.738

Location

 Proximal colon

Ref

  

Ref

  

Ref

  

 Distal colon

0.00

0.997

0.00

0.992

0.00

0.994

 Rectum

2.10

0.08–55.64

0.656

2.71

0.73–10.06

0.136

0.00

0.994

Histology and invasion depth

 AA

Ref

  

Ref

  

Ref

  

 ECRC pTis

0.00

0.997

0.62

0.07–5.52

0.67

1.67

0.17–16.74

0.661

 ECRC pT1a

0.00

0.999

3.18

0.71–14.14

0.129

1.49

0.15–14.90

0.732

 ECRC pT1b

14.88

0.64–343.43

0.092

3.36

0.50–22.75

0.213

35.55

1.44–879.44

0.029

LVI

 negative

Ref

  

Ref

  

Ref

  

 positive

0.67

1.000

2.42

0.19–30.28

0.494

0.00

0.998

  1. HM Horizontal margin, HSP Hot snare polypectomy, EMR Endoscopic mucosal resection, ESD Endoscopic submucosal dissection, AA Advanced adenoma, ECRC Early colorectal cancer, pTis Intramucosal, pT1a Submucosal invasion with less than 1000 um from the muscularis mucosae, pT1b Submucosal invasion with 1000 um more from muscularis mucosae, LVI Lympovascular invasion