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Table 3 The multivariate logistic regression analysis of risk factors for positive VM en bloc resected by HSP, EMR or ESD

From: Influence of early colorectal cancer component on the positive margins after endoscopic resection: a retrospective study

 

Positive VM

HSP

EMR

ESD

 

OR

95%CI

P

OR

95%CI

P

OR

95%CI

P

Size

   1 cm

Ref

  

Ref

  

Ref

  

   2 cm

2.12

0.04–125.82

0.719

0.40

0.10–1.56

0.185

0.68

1.000

  > 2 cm

0.00

0.998

0.43

0.06–3.08

0.401

0.00

0.998

Morphology

 Sessile

Ref

  

Ref

  

Ref

  

 Pedunculated

0.16

0.00–7.89

0.36

0.79

0.21–3.01

0.732

0.26

0.02–3.47

0.307

Location

 Proximal colon

Ref

  

Ref

  

Ref

  

 Distal colon

0.00

0.997

1.4

0.13–15.40

0.785

10.84

0.46–253.85

0.139

 Rectum

2.10

0.08–55.64

0.656

5.62

1.19–26.51

0.029

2.67

0.18–39.06

0.473

Histology and invasion depth

 AA

Ref

  

Ref

  

Ref

  

 ECRC pTis

0.00

0.997

3.99

0.24–65.83

0.333

3.18

0.26–39.60

0.369

 ECRC pT1a

0.00

0.999

23.90

2.55–223.76

0.005

2.96

0.24–36.43

0.396

 ECRC pT1b

14.88

0.64–343.43

0.092

111.84

1.96–1045.55

< 0.001

142.87

7.82–2803.00

0.001

LVI

 negative

Ref

  

Ref

  

Ref

  

 positive

0.67

1.000

3.66

0.56–23.89

0.175

1.12

0.05–23.52

0.942

  1. VM Vertical margin, HSP Hot snare polypectomy, EMR Endoscopic mucosal resection, ESD Endoscopic submucosal dissection, AA Advanced adenoma; ECRC: early colorectal cancer, pTis Intramucosal, pT1a Submucosal invasion with less than 1000 um from the muscularis mucosae, pT1b Submucosal invasion with 1000 um more from muscularis mucosae, LVI Lympovascular invasion